Bateman Lab

Advancing Alzheimer's research

through innovative diagnostic and therapeutic techniques

Our lab is dedicated to researching the causes, diagnosis, and future treatments of Alzheimer’s disease (AD). We use various techniques to directly measure the pathology and pathophysiology of AD in humans. Our team employs a wide range of methods, from basic applications like the quantitative measurement of stable-isotope labeled peptides, to advanced clinical studies focused on diagnostic and therapeutic biomarkers for AD.

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Featured

Tracy Family SILQ Center

Expanding knowledge of proteins associated with Alzheimer’s disease
and other disorders of aging.

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SUNBIRD

Study to Understand Novel Biomarkers in Researching Dementia

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Randall J. Bateman, MD

Principal Investigator

Randall Bateman, MD, is a renowned figure in neurology, holding several prestigious positions, including the Charles F. and Joanne Knight Distinguished Professor of Neurology at WashU Medicine. He directs multiple significant research initiatives such as the Dominantly Inherited Alzheimer Network (DIAN), its Trials Unit (DIAN-TU), and the Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center for Neurodegenerative Biology. His research is primarily focused on understanding the pathophysiology of Alzheimer’s disease and improving its diagnostics and treatments. Bateman also treats dementia patients at the WashU Medicine Memory Diagnostic Center, ensuring a comprehensive blend of research and clinical practice.

Bateman’s lab has achieved significant milestones, including the pioneering of Stable Isotope Labeling Kinetics (SILK) in the central nervous system to study protein kinetics in vivo, and the creation of the first high-precision blood test for detecting Alzheimer’s disease amyloid plaques. Other key contributions of his lab include the advancement of blood tests for Alzheimer’s diagnosis, which rival the accuracy of PET and CSF tests. An active innovator with numerous patents, Bateman co-founded C2N Diagnostics and established several research consortiums to foster academic and industry collaboration in developing neurodegenerative biomarkers. His outstanding work has garnered numerous awards and recognitions, and he is an esteemed member of several prestigious organizations, underlining his influence and leadership in the field of neurodegenerative disease research.

Department profile

Bateman Lab

Advancing Alzheimer's research

Featured

Tracy Family SILQ Center

SUNBIRD

Randall J. Bateman, MD

Principal Investigator

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News

The Breakthrough Blood Test for Alzheimer’s Disease (Links to an external site)

Highly accurate blood test diagnoses Alzheimer’s disease, measures extent of dementia (Links to an external site)

International Alzheimer’s prevention trial in young adults begins (Links to an external site)