Featured publications

Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype

July 1, 2023

Lawler PE, Bollinger JG, Schindler SE, Hodge CR, Iglesias NJ, Krishnan V, Coulton JB, Li Y, Holtzman DM, Bateman RJ. Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype. Anal Biochem. 2023 Jul 1;672:115156. doi: 10.1016/j.ab.2023.115156. Epub 2023 Apr 16. PMID: 37072097.

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer’s Disease

June 1, 2023

Horie K, Li Y, Barthélemy NR, Gordon B, Hassenstab J, Benzinger TLS, Fagan AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, Ikeuchi T, Kasuga K, Noble J, Farlow M, Chhatwal J, Day G, Schofield PR, Masters CL, Levin J, Jucker M, Lee JH, Roh JH, Sato C, Sachdev P, Koyama A, Reyderman L, Bateman RJ, McDade E; and the Dominantly Inherited Alzheimer Network. Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer’s Disease. Ann Neurol. 2023 Jun;93(6):1158-1172. doi: 10.1002/ana.26620. Epub 2023 Mar 16. PMID: 36843330; PMCID: PMC10238659.

Design and feasibility of an Alzheimer’s disease blood test study in a diverse community-based population

May 19, 2023

Li M, Li Y, Schindler SE, Yen D, Sutcliffe S, Babulal GM, Benzinger TLS, Lenze EJ, Bateman RJ. Design and feasibility of an Alzheimer’s disease blood test study in a diverse community-based population. Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13125. Epub ahead of print. PMID: 37204806.

CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease

April 1, 2023

Barthélemy NR, Saef B, Li Y, Gordon BA, He Y, Horie K, Stomrud E, Salvadó G, Janelidze S, Sato C, Ovod V, Henson RL, Fagan AM, Benzinger TLS, Xiong C, Morris JC, Hansson O, Bateman RJ, Schindler SE. CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease. Nat Aging. 2023 Apr;3(4):391-401. doi: 10.1038/s43587-023-00380-7. Epub 2023 Mar 13. PMID: 37117788; PMCID: PMC10154225.

Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS

March 10, 2023

Lucey BP, Liu H, Toedebusch CD, Freund D, Redrick T, Chahin SL, Mawuenyega KG, Bollinger JG, Ovod V, Barthélemy NR, Bateman RJ. Suvorexant Acutely Decreases Tau Phosphorylation and Aβ in the Human CNS. Ann Neurol. 2023 Mar 10. doi: 10.1002/ana.26641. Epub ahead of print. PMID: 36897120.

Acute sleep loss decreases CSF-to-blood clearance of Alzheimer’s disease biomarkers

January 25, 2023

Liu H, Barthélemy NR, Ovod V, Bollinger JG, He Y, Chahin SL, Androff B, Bateman RJ, Lucey BP. Acute sleep loss decreases CSF-to-blood clearance of Alzheimer’s disease biomarkers. Alzheimers Dement. 2023 Jan 25. doi: 10.1002/alz.12930. Epub ahead of print. PMID: 36695437.

Recent publications

  • Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer NetworkWagemann, O., Li, Y., Hassenstab, J., Aschenbrenner, A. J., McKay, N. S., Gordon, B. A., Benzinger, T. L. S., Xiong, C., Cruchaga, C., Renton, A. E., Perrin, R. J., Berman, S. B., Chhatwal, J. P., Farlow, M. R., Day, G. S., Ikeuchi, T., Jucker, M., Lopera, F., Mori, H., Noble, J. M., & 8 othersSánchez-Valle, R., Schofield, P. R., Morris, J. C., Daniels, A., Levin, J., Bateman, R. J., McDade, E. & Llibre-Guerra, J. J., Jan 2024, In: Alzheimer's and Dementia. 20, 1, p. 47-62 16 p.Research output: […]
  • Neuropsychiatric Symptoms in AD: Clinical Trials Targeting Mild Behavioral Impairment: A Report from the International CTAD Task ForceSoto, M., Rosenberg, P., Ballard, C., Vellas, B., Miller, D., Gauthier, S., Carrillo, M. C., Lyketsos, C., Ismail, Z., Abushakra, S., Afshar, M., Agus, S., Aiden, P., Alam, J., Algeciras-Schimnich, A., Andrieu, S., Baruch, A., Bateman, R., Batrla, R., Baudler, M., & 83 othersBell, J., Bittner, T., Bozeat, S., Braunstein, J., Brooks, D., Brooks, T., Bullain, S., Burmeister, J., Carrillo, M., Cho, M., Collins, E., Cook, G., Dague, C., De Santi, S., Doody, R., Dunn, B., Egan, M., Eriksson, S., Esquivel, R., Fagan, […]
  • T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer diseaseRahmani, F., Brier, M. R., Gordon, B. A., McKay, N., Flores, S., Keefe, S., Hornbeck, R., Ances, B., Joseph-Mathurin, N., Xiong, C., Wang, G., Raji, C. A., Libre-Guerra, J. J., Perrin, R. J., McDade, E., Daniels, A., Karch, C., Day, G. S., Brickman, A. M., Fulham, M., & 14 othersJack, C. R., la La Fougère, C., Reischl, G., Schofield, P. R., Oh, H., Levin, J., Vöglein, J., Cash, D. M., Yakushev, I., Ikeuchi, T., Klunk, W. E., Morris, J. C., Bateman, R. J. & Benzinger, T. […]
  • Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer DiseaseShirzadi, Z., Schultz, S. A., Yau, W. Y. W., Joseph-Mathurin, N., Fitzpatrick, C. D., Levin, R., Kantarci, K., Preboske, G. M., Jack, C. R., Farlow, M. R., Hassenstab, J., Jucker, M., Morris, J. C., Xiong, C., Karch, C. M., Levey, A. I., Gordon, B. A., Schofield, P. R., Salloway, S. P., Perrin, R. J., & 26 othersMcDade, E., Levin, J., Cruchaga, C., Allegri, R. F., Fox, N. C., Goate, A., Day, G., Koeppe, R., Chui, H. C., Berman, S., Mori, H., Sanchez-Valle, R., Lee, J. H., Rosa-Neto, P., Ruthirakuhan, […]
  • Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer diseaseKnight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), Alzheimer’s Disease Neuroimaging Initiative (ADNI), ADNI-DOD, A4 Study Team, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, Ali, M., Archer, D. B., Gorijala, P., Western, D., Timsina, J., Fernández, M. V., Chen, G., Gordon, B., Benzinger, T. L. S., Xiong, C., Morris, J. C., Bateman, R. J., Karch, C. M., McDade, E., Sung, Y. J., & 1 othersCruchaga, C., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 68.Research output: Contribution to journal › Article › peer-review
  • Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriersDominantly Inherited Alzheimer Network (DIAN), Brase, L., You, S. F., D’Oliveira Albanus, R., Novotny, B. C., Soriano-Tarraga, C., Dykstra, T., Fernandez, M. V., Budde, J. P., Bergmann, K., Morris, J. C., Bateman, R. J., Perrin, R. J., McDade, E., Xiong, C., Kipnis, J., Karch, C. M., Benitez, B. A. & Harari, O., Dec 2023, In: Nature communications. 14, 1, 2314.Research output: Contribution to journal › Article › peer-review
  • Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trialDelrieu, J., Vellas, B., Guyonnet, S., Cantet, C., Ovod, V., Li, Y., Bollinger, J., Bateman, R. & Andrieu, S., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 183.Research output: Contribution to journal › Article › peer-review
  • Advanced structural brain aging in preclinical autosomal dominant Alzheimer diseaseMillar, P. R., Gordon, B. A., Wisch, J. K., Schultz, S. A., Benzinger, T. L., Cruchaga, C., Hassenstab, J. J., Ibanez, L., Karch, C., Llibre-Guerra, J. J., Morris, J. C., Perrin, R. J., Supnet-Bell, C., Xiong, C., Allegri, R. F., Berman, S. B., Chhatwal, J. P., Chrem Mendez, P. A., Day, G., Hofmann, A., & 13 othersIkeuchi, T., Jucker, M., Lee, J. H., Levin, J., Lopera, F., Niimi, Y., Sánchez-González, V. J., Schofield, P. R., Sosa-Ortiz, A. L., Vöglein, J., Bateman, R. J., Ances, B. M. & McDade, E. M., Dec […]
  • A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s diseaseMerrihew, G. E., Park, J., Plubell, D., Searle, B. C., Keene, C. D., Larson, E. B., Bateman, R., Perrin, R. J., Chhatwal, J. P., Farlow, M. R., McLean, C. A., Ghetti, B., Newell, K. L., Frosch, M. P., Montine, T. J. & MacCoss, M. J., Dec 2023, In: Scientific data. 10, 1, 206.Research output: Contribution to journal › Article › peer-review
  • Tau accumulation in autosomal dominant Alzheimer’s disease: a longitudinal [18F]flortaucipir studyO’Connor, A., Cash, D. M., Poole, T., Markiewicz, P. J., Fraser, M. R., Malone, I. B., Jiao, J., Weston, P. S. J., Flores, S., Hornbeck, R., McDade, E., Schöll, M., Gordon, B. A., Bateman, R. J., Benzinger, T. L. S. & Fox, N. C., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 99.Research output: Contribution to journal › Article › peer-review

Publication collections

Complete bibliography